Special Technologies

Special Technologies

The standard reactions that are listed under Performed Reactions. In particular, through several decades of experience, we have accumulated in-depth knowledge for the following highly specific reaction types.

High Pressure Reaction

We can perform reactions up to a pressure of 100 bar (1,400 psi) in especially designed reactors with a reaction volume of 1,000 l and up to 250 °C. This reaction comprises the use of gaseous material and low boiling solvents at elevated temperature, as well as Diels-Alder-Reactions, where the equilibrium can be moved into the right direction by application of pressure.


The reaction with hydrogen needs special precautions and a specific safety design of the equipment used. This has all been fulfilled on our premises, and only very skilled workers are carrying out such hazardous reactions. Hydrogenation can be done using Raney-Nickel, as well as all kind of precious metal catalysts, predominantly in a heterogeneous system. Also homogeneous catalysis can be carried out, even though the work-up procedure is very often more complicated. The pressure that can be reached is 100 bar (1,400 psi) with a temperature range up to 250 °C. Reaction volumes are 1,000 l (100 bar) up to 6,000 l (20 bar).

Grignard Reaction

We are equipped with especially designed reactors for the Grignard reagent itself, starting from the organic halide and magnesium. As an advantage, we are consequently not limited to the few available reagent solutions, and are very flexible in carrying out a variety of Grignard reactions.

Especially the initiation of the reaction can be difficult and challenging. Over decades we have acquired the technical Know-How to carry out this reaction successfully, safely, and efficiently.

Low temperature technology

Many chemical reactions are done in a temperature range of -15 °C to 150 °C. Additionally some reactions may be carried out at very low temperature only to yield the desired product. The newly installed cryogenic technology now allows carrying out reactions as cold as -90 °C and opens herewith a new dimension for organic synthesis. We just want to mention metallation reactions with organo metallic compounds, such as Butyllithium, or crypto bases like Lithiumdiisoproylamide (LDA). Till today only reactions down to -15 °C could be carried out.

The newly installed Train 13 in our state-of-the-art MPA-P3 production unit has now been expanded with this additional cryogenic reactor with a operational volume of 2,500 Litres. Beside the low temperature conditions it can also be used as hydrogenation reactor for pressures up to 25 bar. The work-up of the reaction will be done in the reactor (crystaller) located below the cryogenic unit. The cooling of the reactor is done by means of a heat transfer liquid that further is pre-cooled by using liquid nitrogen (-196 °C).

With the introduction of the low temperature technology, CU CHEMIE UETIKON has expanded its spectrum of reactions and completes the offer for our customers essentially.